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4-Week repeated oral dose toxicity study of 1,4-dichlorobutane in rats

The present study investigated the potential subacute toxicity of 1,4-dichlorobutane by a 4-week repeated oral dose in Sprague-Dawley rats. The test article was administered once daily by gavage to male rats at dose levels of 0, 100, 300, and 1,000 mg/kg/day for 4 weeks. All rats were sacrificed at...

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Detalles Bibliográficos
Autores principales: Yu, Wook-Joon, Lee, In-Chul, Lee, Jinsoo, Lee, Sang-Min, Kim, Sung-Hwan, Baek, Hyung-Seon, Moon, Changjong, Kim, Sung-Ho, Chung, Yong-Hyun, Kim, Jong-Choon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association for Laboratory Animal Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616209/
https://www.ncbi.nlm.nih.gov/pubmed/23573108
http://dx.doi.org/10.5625/lar.2013.29.1.48