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Structural and functional association of androgen receptor with telomeres in prostate cancer cells

Telomeres protect the ends of linear chromosomes from being recognized as damaged DNA, and telomere stability is required for genome stability. Here we demonstrate that telomere stability in androgen receptor (AR)-positive LNCaP human prostate cancer cells is dependent on AR and androgen, as AR inac...

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Detalles Bibliográficos
Autores principales: Zhou, Junying, Richardson, Michelle, Reddy, Vidyavathi, Menon, Mani, Barrack, Evelyn R., Reddy, G. Prem-Veer, Kim, Sahn-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616228/
https://www.ncbi.nlm.nih.gov/pubmed/23363843