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Chronic oxidative stress upregulates Drusen-related protein expression in adult human RPE stem cell-derived RPE cells: A novel culture model for dry AMD

PURPOSE: The goal of this study was to examine changes in the expression of transcripts and proteins associated with drusen in Age-related Macular Degeneration (AMD) after exposing human retinal pigment epithelium (hRPE) cells to chronic oxidative stress. METHODS: Primary adult human RPE cells were...

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Detalles Bibliográficos
Autores principales: Rabin, David M., Rabin, Richard L., Blenkinsop, Timothy A., Temple, Sally, Stern, Jeffrey H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616231/
https://www.ncbi.nlm.nih.gov/pubmed/23257616