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Rules for the recognition of dilysine retrieval motifs by coatomer

Cytoplasmic dilysine motifs on transmembrane proteins are captured by coatomer α-COP and β′-COP subunits and packaged into COPI-coated vesicles for Golgi-to-ER retrieval. Numerous ER/Golgi proteins contain K(x)Kxx motifs, but the rules for their recognition are unclear. We present crystal structures...

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Detalles Bibliográficos
Autores principales: Ma, Wenfu, Goldberg, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616288/
https://www.ncbi.nlm.nih.gov/pubmed/23481256
http://dx.doi.org/10.1038/emboj.2013.41