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Nox4 as a potential therapeutic target for treatment of uremic toxicity associated to chronic kidney disease
Watanabe et al. report that Nox4 NADPH oxidase catalytic moiety and the subunit p22(phox) mediate the increase in oxidative stress and human tubular epithelial cell injury induced by p-cresyl sulfate, a protein-bound uremic toxin. These findings could be instrumental for the design of novel therapeu...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616333/ https://www.ncbi.nlm.nih.gov/pubmed/23538692 http://dx.doi.org/10.1038/ki.2012.434 |