XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells

Autophagy is activated to maintain cellular energy homeostasis in response to nutrient starvation. However, autophagy is not persistently activated, which is poorly understood at a mechanistic level. Here, we report that turnover of FoxO1 is involved in the dynamic autophagic process caused by gluta...

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Detalles Bibliográficos
Autores principales: Zhao, Ying, Li, Xue, Cai, Mu-Yan, Ma, Ke, Yang, Jing, Zhou, Jingyi, Fu, Wan, Wei, Fu-Zheng, Wang, Lina, Xie, Dan, Zhu, Wei-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616429/
https://www.ncbi.nlm.nih.gov/pubmed/23277279
http://dx.doi.org/10.1038/cr.2013.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616429/
https://www.ncbi.nlm.nih.gov/pubmed/23277279
http://dx.doi.org/10.1038/cr.2013.2

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