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XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells
Autophagy is activated to maintain cellular energy homeostasis in response to nutrient starvation. However, autophagy is not persistently activated, which is poorly understood at a mechanistic level. Here, we report that turnover of FoxO1 is involved in the dynamic autophagic process caused by gluta...
Autores principales: | Zhao, Ying, Li, Xue, Cai, Mu-Yan, Ma, Ke, Yang, Jing, Zhou, Jingyi, Fu, Wan, Wei, Fu-Zheng, Wang, Lina, Xie, Dan, Zhu, Wei-Guo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616429/ https://www.ncbi.nlm.nih.gov/pubmed/23277279 http://dx.doi.org/10.1038/cr.2013.2 |
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