Trinucleotide repeat expansions catalyzed by human cell-free extracts

Trinucleotide repeat expansions cause 17 heritable human neurological disorders. In some diseases, somatic expansions occur in non-proliferating tissues such as brain where DNA replication is limited. This finding stimulated significant interest in replication-independent expansion mechanisms. Aberr...

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Detalles Bibliográficos
Autores principales: Stevens, Jennifer R, Lahue, Elaine E, Li, Guo-Min, Lahue, Robert S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616437/
https://www.ncbi.nlm.nih.gov/pubmed/23337586
http://dx.doi.org/10.1038/cr.2013.12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616437/
https://www.ncbi.nlm.nih.gov/pubmed/23337586
http://dx.doi.org/10.1038/cr.2013.12

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