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Trinucleotide repeat expansions catalyzed by human cell-free extracts
Trinucleotide repeat expansions cause 17 heritable human neurological disorders. In some diseases, somatic expansions occur in non-proliferating tissues such as brain where DNA replication is limited. This finding stimulated significant interest in replication-independent expansion mechanisms. Aberr...
Autores principales: | Stevens, Jennifer R, Lahue, Elaine E, Li, Guo-Min, Lahue, Robert S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616437/ https://www.ncbi.nlm.nih.gov/pubmed/23337586 http://dx.doi.org/10.1038/cr.2013.12 |
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