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Overexpression of paxillin induced by miR-137 suppression promotes tumor progression and metastasis in colorectal cancer

The deregulation of paxillin (PXN) has been involved in the progression and metastasis of different malignancies including colorectal cancer (CRC). miR-137 is frequently suppressed in CRC. PXN is predicted to be a direct target of miR-137 in CRC cells. On this basis, we hypothesized that overexpress...

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Detalles Bibliográficos
Autores principales: Chen, Dong-Liang, Wang, De-Shen, Wu, Wen-Jing, Zeng, Zhao-Lei, Luo, Hui-Yan, Qiu, Miao-Zhen, Ren, Chao, Zhang, Dong-Sheng, Wang, Zhi-Qiang, Wang, Feng-Hua, Li, Yu-Hong, Kang, Tie-Bang, Xu, Rui-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616669/
https://www.ncbi.nlm.nih.gov/pubmed/23275153
http://dx.doi.org/10.1093/carcin/bgs400