The small molecule Retro-1 enhances the pharmacological actions of antisense and splice switching oligonucleotides

The attainment of strong pharmacological effects with oligonucleotides is hampered by inefficient access of these molecules to their sites of action in the cytosol or nucleus. Attempts to address this problem with lipid or polymeric delivery systems have been only partially successful. Here, we desc...

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Detalles Bibliográficos
Autores principales: Ming, Xin, Carver, Kyle, Fisher, Michael, Noel, Romain, Cintrat, Jean-Christophe, Gillet, Daniel, Barbier, Julien, Cao, Canhong, Bauman, John, Juliano, Rudolph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616695/
https://www.ncbi.nlm.nih.gov/pubmed/23396438
http://dx.doi.org/10.1093/nar/gkt066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616695/
https://www.ncbi.nlm.nih.gov/pubmed/23396438
http://dx.doi.org/10.1093/nar/gkt066

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