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The small molecule Retro-1 enhances the pharmacological actions of antisense and splice switching oligonucleotides
The attainment of strong pharmacological effects with oligonucleotides is hampered by inefficient access of these molecules to their sites of action in the cytosol or nucleus. Attempts to address this problem with lipid or polymeric delivery systems have been only partially successful. Here, we desc...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616695/ https://www.ncbi.nlm.nih.gov/pubmed/23396438 http://dx.doi.org/10.1093/nar/gkt066 |