Cargando…

A systemic transcriptome analysis reveals the regulation of neural stem cell maintenance by an E2F1–miRNA feedback loop

Stem cell fate decisions are controlled by a molecular network in which transcription factors and miRNAs are of key importance. To systemically investigate their impact on neural stem cell (NSC) maintenance and neuronal commitment, we performed a high-throughput mRNA and miRNA profiling and isolated...

Descripción completa

Detalles Bibliográficos
Autores principales: Palm, Thomas, Hemmer, Kathrin, Winter, Julia, Fricke, Inga B., Tarbashevich, Katsiaryna, Sadeghi Shakib, Fereshteh, Rudolph, Ina-Maria, Hillje, Anna-Lena, De Luca, Paola, Bahnassawy, Lamia'a, Madel, Rabea, Viel, Thomas, De Siervi, Adriana, Jacobs, Andreas H., Diederichs, Sven, Schwamborn, Jens C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616707/
https://www.ncbi.nlm.nih.gov/pubmed/23396440
http://dx.doi.org/10.1093/nar/gkt070