Cargando…

A systemic transcriptome analysis reveals the regulation of neural stem cell maintenance by an E2F1–miRNA feedback loop

Stem cell fate decisions are controlled by a molecular network in which transcription factors and miRNAs are of key importance. To systemically investigate their impact on neural stem cell (NSC) maintenance and neuronal commitment, we performed a high-throughput mRNA and miRNA profiling and isolated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Palm, Thomas, Hemmer, Kathrin, Winter, Julia, Fricke, Inga B., Tarbashevich, Katsiaryna, Sadeghi Shakib, Fereshteh, Rudolph, Ina-Maria, Hillje, Anna-Lena, De Luca, Paola, Bahnassawy, Lamia'a, Madel, Rabea, Viel, Thomas, De Siervi, Adriana, Jacobs, Andreas H., Diederichs, Sven, Schwamborn, Jens C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616707/ https://www.ncbi.nlm.nih.gov/pubmed/23396440 http://dx.doi.org/10.1093/nar/gkt070

Ejemplares similares

TRIM32 modulates pluripotency entry and exit by directly regulating Oct4 stability
por: Bahnassawy, Lamia’a, et al.
Publicado: (2015)

TRIM32-dependent transcription in adult neural progenitor cells regulates neuronal differentiation
por: Hillje, A-L, et al.
Publicado: (2013)

A complex of the ubiquitin ligase TRIM32 and the deubiquitinase USP7 balances the level of c-Myc ubiquitination and thereby determines neural stem cell fate specification
por: Nicklas, Sarah, et al.
Publicado: (2018)

The mitochondrial protein Sod2 is important for the migration, maintenance, and fitness of germ cells
por: Tarbashevich, Katsiaryna, et al.
Publicado: (2023)

Inhibition of signaling between human CXCR4 and zebrafish ligands by the small molecule IT1t impairs the formation of triple-negative breast cancer early metastases in a zebrafish xenograft model
por: Tulotta, Claudia, et al.
Publicado: (2016)

Retention of paternal DNA methylome in the developing zebrafish germline
por: Skvortsova, Ksenia, et al.
Publicado: (2019)

The neural stem cell fate determinant TRIM32 regulates complex behavioral traits
por: Hillje, Anna-Lena, et al.
Publicado: (2015)

Primordial germ cells adjust their protrusion type while migrating in different tissue contexts in vivo
por: Truszkowski, Lukasz, et al.
Publicado: (2023)

The RNA helicase DDX6 regulates cell-fate specification in neural stem cells via miRNAs
por: Nicklas, Sarah, et al.
Publicado: (2015)

PKA and PKC Modulators Affect Ion Channel Function and Internalization of Recombinant Alpha1 and Alpha1-Beta Glycine Receptors
por: Breitinger, Ulrike, et al.
Publicado: (2018)

Dynamic filopodia are required for chemokine-dependent intracellular polarization during guided cell migration in vivo
por: Meyen, Dana, et al.
Publicado: (2015)

Regulatory feedback loop between TP73 and TRIM32
por: Gonzalez-Cano, L, et al.
Publicado: (2013)

Liver Organoids as an In Vitro Model to Study Primary Liver Cancer
por: De Siervi, Silvia, et al.
Publicado: (2023)

Anti-inflammatory treatment induced regenerative oligodendrogenesis in parkinsonian mice
por: Worlitzer, Maik MA, et al.
Publicado: (2012)

Spatial organization and function of RNA molecules within phase-separated condensates are controlled by Dnd1
por: Westerich, Kim Joana, et al.
Publicado: (2023)

Argonaute-3 activates the let-7a passenger strand microRNA
por: Winter, Julia, et al.
Publicado: (2013)

E-cadherin focuses protrusion formation at the front of migrating cells by impeding actin flow
por: Grimaldi, Cecilia, et al.
Publicado: (2020)

Chronic Liver Disease: Latest Research in Pathogenesis, Detection and Treatment
por: De Siervi, Silvia, et al.
Publicado: (2023)

Synovial sarcoma of the mandible
por: Khalili, Maryam, et al.
Publicado: (2012)

Repulsive cues combined with physical barriers and cell–cell adhesion determine progenitor cell positioning during organogenesis
por: Paksa, Azadeh, et al.
Publicado: (2016)

Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis
por: Cao, Jiahui, et al.
Publicado: (2017)

Cerebro: interactive visualization of scRNA-seq data
por: Hillje, Roman, et al.
Publicado: (2020)

Substantial heterogeneity of inflammatory cytokine production and its inhibition by a triple cocktail of toll-like receptor blockers in early sepsis
por: Buys, Willem, et al.
Publicado: (2023)

Functional characterization of a single nucleotide polymorphism associated with Alzheimer’s disease in a hiPSC-based neuron model
por: Stolzenburg, Lindsay R., et al.
Publicado: (2023)

Rapid and robust generation of long-term self-renewing human neural stem cells with the ability to generate mature astroglia
por: Palm, Thomas, et al.
Publicado: (2015)

Comunicación en la Correspondencia Empresarial
por: De Gonzalez Saiffe, Ma.del carmen
Publicado: (1990)

Acute and Subacute Toxicity of Safranal, a Constituent of Saffron, in Mice and Rats
por: Hosseinzadeh, Hossein, et al.
Publicado: (2013)

CD44 and CD74: The promising candidates for molecular targeted therapy in oral squamous cell carcinoma
por: Shakib, Pouyan Amini, et al.
Publicado: (2015)

Comparison of triploid and diploid rainbow trout (Oncorhynchus mykiss) fine-scale movement, migration and catchability in lowland lakes of western Washington
por: Pease, Jessica E., et al.
Publicado: (2023)

Relative Expression of OCT4, SOX2 and NANOG in Oral Squamous Cell Carcinoma Versus Adjacent Non- Tumor Tissue
por: Baghai Naini, Fereshteh, et al.
Publicado: (2019)

XenoCell: classification of cellular barcodes in single cell experiments from xenograft samples
por: Cheloni, Stefano, et al.
Publicado: (2021)

Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells
por: Monzel, Anna S., et al.
Publicado: (2017)

Is thromboprophylaxis effective in reducing the pulmonary thromboembolism?
por: Rajabi, Fereshteh, et al.
Publicado: (2012)

Transcriptional regulation of BRCA1 expression by a metabolic switch
por: Di, Li-Jun, et al.
Publicado: (2010)

δ-Aminolevulinic acid cytotoxic effects on human hepatocarcinoma cell lines
por: De Siervi, Adriana, et al.
Publicado: (2002)

Precision medicine technology hype or reality? The example of computer-guided dosing
por: Polasek, Thomas M., et al.
Publicado: (2019)

Immune hyporeactivity to bacteria and multiple TLR-ligands, yet no response to checkpoint inhibition in patients just after meeting Sepsis-3 criteria
por: Bick, Alexandra, et al.
Publicado: (2022)

Heme Oxygenase-1 (HO-1) Expression in Prostate Cancer Cells Modulates the Oxidative Response in Bone Cells
por: Ferrando, Mercedes, et al.
Publicado: (2013)

Loop-miRs: active microRNAs generated from single-stranded loop regions
por: Winter, Julia, et al.
Publicado: (2013)

XTT assay of ex vivo saliva biofilms to test antimicrobial influences
por: Koban, Ina, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_d4k6t4mdk7lsr97i5bgo9vs01t