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Structure–function relationships of two paralogous single-stranded DNA-binding proteins from Streptomyces coelicolor: implication of SsbB in chromosome segregation during sporulation

The linear chromosome of Streptomyces coelicolor contains two paralogous ssb genes, ssbA and ssbB. Following mutational analysis, we concluded that ssbA is essential, whereas ssbB plays a key role in chromosome segregation during sporulation. In the ssbB mutant, ∼30% of spores lacked DNA. The two ss...

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Detalles Bibliográficos
Autores principales: Paradzik, Tina, Ivic, Nives, Filic, Zelimira, Manjasetty, Babu A., Herron, Paul, Luic, Marija, Vujaklija, Dusica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616714/
https://www.ncbi.nlm.nih.gov/pubmed/23393191
http://dx.doi.org/10.1093/nar/gkt050