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The RNA exosome complex central channel controls both exonuclease and endonuclease Dis3 activities in vivo and in vitro
The RNA exosome is an essential ribonuclease complex involved in RNA processing and decay. It consists of a 9-subunit catalytically inert ring composed of six RNase PH-like proteins forming a central channel and three cap subunits with KH/S1 domains located at the top. The yeast exosome catalytic ac...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616716/ https://www.ncbi.nlm.nih.gov/pubmed/23404585 http://dx.doi.org/10.1093/nar/gkt060 |