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The RNA exosome complex central channel controls both exonuclease and endonuclease Dis3 activities in vivo and in vitro

The RNA exosome is an essential ribonuclease complex involved in RNA processing and decay. It consists of a 9-subunit catalytically inert ring composed of six RNase PH-like proteins forming a central channel and three cap subunits with KH/S1 domains located at the top. The yeast exosome catalytic ac...

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Detalles Bibliográficos
Autores principales: Drążkowska, Karolina, Tomecki, Rafał, Stoduś, Krystian, Kowalska, Katarzyna, Czarnocki-Cieciura, Mariusz, Dziembowski, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616716/
https://www.ncbi.nlm.nih.gov/pubmed/23404585
http://dx.doi.org/10.1093/nar/gkt060