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Disclosure of a structural milieu for the proximity ligation reveals the elusive nature of an active chromatin hub

The current progress in the study of the spatial organization of interphase chromosomes became possible owing to the development of the chromosome conformation capture (3C) protocol. The crucial step of this protocol is the proximity ligation—preferential ligation of DNA fragments assumed to be join...

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Detalles Bibliográficos
Autores principales: Gavrilov, Alexey A., Gushchanskaya, Ekaterina S., Strelkova, Olga, Zhironkina, Oksana, Kireev, Igor I., Iarovaia, Olga V., Razin, Sergey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616722/
https://www.ncbi.nlm.nih.gov/pubmed/23396278
http://dx.doi.org/10.1093/nar/gkt067