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Disclosure of a structural milieu for the proximity ligation reveals the elusive nature of an active chromatin hub
The current progress in the study of the spatial organization of interphase chromosomes became possible owing to the development of the chromosome conformation capture (3C) protocol. The crucial step of this protocol is the proximity ligation—preferential ligation of DNA fragments assumed to be join...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616722/ https://www.ncbi.nlm.nih.gov/pubmed/23396278 http://dx.doi.org/10.1093/nar/gkt067 |