Exploring sRNA-mediated gene silencing mechanisms using artificial small RNAs derived from a natural RNA scaffold in Escherichia coli

An artificial small RNA (afsRNA) scaffold was designed from an Escherichia coli sRNA, SibC. Using the lacZ reporter system, the gene silencing effects of afsRNAs were examined to explore the sRNA-mediated gene-silencing mechanisms in E. coli. Substitution of the original target recognition sequence...

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Detalles Bibliográficos
Autores principales: Park, Hongmarn, Bak, Geunu, Kim, Sun Chang, Lee, Younghoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616725/
https://www.ncbi.nlm.nih.gov/pubmed/23393193
http://dx.doi.org/10.1093/nar/gkt061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616725/
https://www.ncbi.nlm.nih.gov/pubmed/23393193
http://dx.doi.org/10.1093/nar/gkt061

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