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Isolation and identification of cell-specific microRNAs targeting a messenger RNA using a biotinylated anti-sense oligonucleotide capture affinity technique

MicroRNAs (miRNAs) are small non-coding RNAs that regulate expression by translational repression or messenger RNA (mRNA) degradation. Although numerous bioinformatic prediction models exist to identify miRNA–mRNA interactions, experimental validation of bona fide interactions can be difficult and l...

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Detalles Bibliográficos
Autores principales: Hassan, Tidi, Smith, Stephen G. J., Gaughan, Kevin, Oglesby, Irene K., O’Neill, Shane, McElvaney, Noel G., Greene, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616726/
https://www.ncbi.nlm.nih.gov/pubmed/23325846
http://dx.doi.org/10.1093/nar/gks1466