Dicer-independent processing of short hairpin RNAs

Short hairpin RNAs (shRNAs) are widely used to induce RNA interference (RNAi). We tested a variety of shRNAs that differed in stem length and terminal loop size and revealed strikingly different RNAi activities and shRNA-processing patterns. Interestingly, we identified a specific shRNA design that...

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Detalles Bibliográficos
Autores principales: Liu, Ying Poi, Schopman, Nick C. T., Berkhout, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616727/
https://www.ncbi.nlm.nih.gov/pubmed/23376931
http://dx.doi.org/10.1093/nar/gkt036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616727/
https://www.ncbi.nlm.nih.gov/pubmed/23376931
http://dx.doi.org/10.1093/nar/gkt036

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