Cargando…

Sequence-specific inhibition of Dicer measured with a force-based microarray for RNA ligands

Malfunction of protein translation causes many severe diseases, and suitable correction strategies may become the basis of effective therapies. One major regulatory element of protein translation is the nuclease Dicer that cuts double-stranded RNA independently of the sequence into pieces of 19–22 b...

Descripción completa

Detalles Bibliográficos
Autores principales: Limmer, Katja, Aschenbrenner, Daniela, Gaub, Hermann E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616731/
https://www.ncbi.nlm.nih.gov/pubmed/23303774
http://dx.doi.org/10.1093/nar/gks1455