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Angiotensin Converting Enzyme Inhibitors Mitigate Collagen Synthesis Induced by a Single Dose of Radiation to the Whole Thorax

Our long-term goal is to use angiotensin converting enzyme (ACE) inhibitors to mitigate the increase in lung collagen synthesis that is induced by irradiation to the lung, which could result from accidental exposure or radiological terrorism. Rats (WAG/RijCmcr) were given a single dose of 13 Gy (dos...

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Detalles Bibliográficos
Autores principales: Kma, Lakhan, Gao, Feng, Fish, Brian L., Moulder, John E., Jacobs, Elizabeth R., Medhora, Meetha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Radiation Research Society and Japanese Society for Therapeutic Radiology and Oncology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616750/
https://www.ncbi.nlm.nih.gov/pubmed/22302041
http://dx.doi.org/10.1269/jrr.11035