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Coagulopathy triggered autoimmunity: experimental antiphospholipid syndrome in factor V Leiden mice

BACKGROUND: We investigated interactions between genetically and autoimmune-mediated coagulopathies by inducing experimental antiphospholipid syndrome (eAPS) in mice carrying the factor V Leiden (FVL) mutation. METHODS: eAPS was induced in heterozygous and homozygous FVL transgenic mice (C57BL/6 bac...

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Detalles Bibliográficos
Autores principales: Katzav, Aviva, Grigoriadis, Nikolaos C, Ebert, Tania, Touloumi, Olga, Blank, Miri, Pick, Chaim G, Shoenfeld, Yehuda, Chapman, Joab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616820/
https://www.ncbi.nlm.nih.gov/pubmed/23566870
http://dx.doi.org/10.1186/1741-7015-11-92