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Iron-Responsive miR-485-3p Regulates Cellular Iron Homeostasis by Targeting Ferroportin
Ferroportin (FPN) is the only known cellular iron exporter in mammalian cells and plays a critical role in the maintenance of both cellular and systemic iron balance. During iron deprivation, the translation of FPN is repressed by iron regulatory proteins (IRPs), which bind to the 5′ untranslated re...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616902/ https://www.ncbi.nlm.nih.gov/pubmed/23593016 http://dx.doi.org/10.1371/journal.pgen.1003408 |