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Genome-wide methylation profiling of the bronchial mucosa of asthmatics: relationship to atopy
BACKGROUND: Asthma is a common respiratory disease that is characterized by bronchial hyperresponsiveness and airway obstruction due to chronic airway inflammation. Atopic asthma is a typical IgE-mediated disease in which the enhanced production of IgE is driven by the activation of Th2 cells, which...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616917/ https://www.ncbi.nlm.nih.gov/pubmed/23521807 http://dx.doi.org/10.1186/1471-2350-14-39 |