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DNA Double-Strand Breaks Coupled with PARP1 and HNRNPA2B1 Binding Sites Flank Coordinately Expressed Domains in Human Chromosomes

Genome instability plays a key role in multiple biological processes and diseases, including cancer. Genome-wide mapping of DNA double-strand breaks (DSBs) is important for understanding both chromosomal architecture and specific chromosomal regions at DSBs. We developed a method for precise genome-...

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Detalles Bibliográficos
Autores principales: Tchurikov, Nickolai A., Kretova, Olga V., Fedoseeva, Daria M., Sosin, Dmitri V., Grachev, Sergei A., Serebraykova, Marina V., Romanenko, Svetlana A., Vorobieva, Nadezhda V., Kravatsky, Yuri V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616924/
https://www.ncbi.nlm.nih.gov/pubmed/23593027
http://dx.doi.org/10.1371/journal.pgen.1003429