The JAK-STAT Transcriptional Regulator, STAT-5, Activates the ATM DNA Damage Pathway to Induce HPV 31 Genome Amplification upon Epithelial Differentiation

High-risk human papillomavirus (HPV) must evade innate immune surveillance to establish persistent infections and to amplify viral genomes upon differentiation. Members of the JAK-STAT family are important regulators of the innate immune response and HPV proteins downregulate expression of STAT-1 to...

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Detalles Bibliográficos
Autores principales: Hong, Shiyuan, Laimins, Laimonis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616964/
https://www.ncbi.nlm.nih.gov/pubmed/23593005
http://dx.doi.org/10.1371/journal.ppat.1003295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616964/
https://www.ncbi.nlm.nih.gov/pubmed/23593005
http://dx.doi.org/10.1371/journal.ppat.1003295

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