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TNF-α promotes cerebral pericyte remodeling in vitro, via a switch from α1 to α2 integrins

BACKGROUND: There is increasing evidence to suggest that pericytes play a crucial role in regulating the remodeling state of blood vessels. As cerebral pericytes are embedded within the extracellular matrix (ECM) of the vascular basal lamina, it is important to understand how individual ECM componen...

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Detalles Bibliográficos
Autores principales: Tigges, Ulrich, Boroujerdi, Amin, Welser-Alves, Jennifer V, Milner, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616978/
https://www.ncbi.nlm.nih.gov/pubmed/23448258
http://dx.doi.org/10.1186/1742-2094-10-33