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Comparison of SIV and HIV-1 Genomic RNA Structures Reveals Impact of Sequence Evolution on Conserved and Non-Conserved Structural Motifs

RNA secondary structure plays a central role in the replication and metabolism of all RNA viruses, including retroviruses like HIV-1. However, structures with known function represent only a fraction of the secondary structure reported for HIV-1(NL4-3). One tool to assess the importance of RNA struc...

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Detalles Bibliográficos
Autores principales: Pollom, Elizabeth, Dang, Kristen K., Potter, E. Lake, Gorelick, Robert J., Burch, Christina L., Weeks, Kevin M., Swanstrom, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616985/
https://www.ncbi.nlm.nih.gov/pubmed/23593004
http://dx.doi.org/10.1371/journal.ppat.1003294