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Repeat-encoded poly-Q tracts show statistical commonalities across species

BACKGROUND: Among repetitive genomic sequence, the class of tri-nucleotide repeats has received much attention due to their association with human diseases. Tri-nucleotide repeat diseases are caused by excessive sequence length variability; diseases such as Huntington’s disease and Fragile X syndrom...

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Detalles Bibliográficos
Autores principales: Willadsen, Kai, Cao, Minh Duc, Wiles, Janet, Balasubramanian, Sureshkumar, Bodén, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617014/
https://www.ncbi.nlm.nih.gov/pubmed/23374135
http://dx.doi.org/10.1186/1471-2164-14-76