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Evolutionary Capacitance and Control of Protein Stability in Protein-Protein Interaction Networks
In addition to their biological function, protein complexes reduce the exposure of the constituent proteins to the risk of undesired oligomerization by reducing the concentration of the free monomeric state. We interpret this reduced risk as a stabilization of the functional state of the protein. We...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617028/ https://www.ncbi.nlm.nih.gov/pubmed/23592969 http://dx.doi.org/10.1371/journal.pcbi.1003023 |