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Genetic and Genomic Architecture of the Evolution of Resistance to Antifungal Drug Combinations

The evolution of drug resistance in fungal pathogens compromises the efficacy of the limited number of antifungal drugs. Drug combinations have emerged as a powerful strategy to enhance antifungal efficacy and abrogate drug resistance, but the impact on the evolution of drug resistance remains large...

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Detalles Bibliográficos
Autores principales: Hill, Jessica A., Ammar, Ron, Torti, Dax, Nislow, Corey, Cowen, Leah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617151/
https://www.ncbi.nlm.nih.gov/pubmed/23593013
http://dx.doi.org/10.1371/journal.pgen.1003390