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Genetic and Genomic Architecture of the Evolution of Resistance to Antifungal Drug Combinations
The evolution of drug resistance in fungal pathogens compromises the efficacy of the limited number of antifungal drugs. Drug combinations have emerged as a powerful strategy to enhance antifungal efficacy and abrogate drug resistance, but the impact on the evolution of drug resistance remains large...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617151/ https://www.ncbi.nlm.nih.gov/pubmed/23593013 http://dx.doi.org/10.1371/journal.pgen.1003390 |