Fulvestrant-Induced Cell Death and Proteasomal Degradation of Estrogen Receptor α Protein in MCF-7 Cells Require the CSK c-Src Tyrosine Kinase

Fulvestrant is a representative pure antiestrogen and a Selective Estrogen Receptor Down-regulator (SERD). In contrast to the Selective Estrogen Receptor Modulators (SERMs) such as 4-hydroxytamoxifen that bind to estrogen receptor α (ERα) as antagonists or partial agonists, fulvestrant causes protea...

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Detalles Bibliográficos
Autores principales: Yeh, Wei-Lan, Shioda, Keiko, Coser, Kathryn R., Rivizzigno, Danielle, McSweeney, Kristen R., Shioda, Toshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617152/
https://www.ncbi.nlm.nih.gov/pubmed/23593342
http://dx.doi.org/10.1371/journal.pone.0060889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617152/
https://www.ncbi.nlm.nih.gov/pubmed/23593342
http://dx.doi.org/10.1371/journal.pone.0060889

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