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-374 T/A RAGE Polymorphism Is Associated with Chronic Kidney Disease Progression in Subjects Affected by Nephrocardiovascular Disease

BACKGROUND: Chronic kidney disease (CKD) patients present elevated advanced glycation end products (AGEs) blood levels. AGEs promote inflammation through binding to their receptor (RAGE), located on the membrane of mesangial cells, endothelial cells and macrophages. Several genetic polymorphisms inf...

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Detalles Bibliográficos
Autores principales: Baragetti, Ivano, Norata, Giuseppe Danilo, Sarcina, Cristina, Baragetti, Andrea, Rastelli, Francesco, Buzzi, Laura, Grigore, Liliana, Garlaschelli, Katia, Pozzi, Claudio, Catapano, Alberico Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617170/
https://www.ncbi.nlm.nih.gov/pubmed/23593165
http://dx.doi.org/10.1371/journal.pone.0060089