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Sulfatide Regulates Caspase-3-Independent Apoptosis of Influenza A Virus through Viral PB1-F2 Protein

Influenza A virus (IAV) generally causes caspase-dependent apoptosis based on caspase-3 activation, resulting in nuclear export of newly synthesized viral nucleoprotein (NP) and elevated virus replication. Sulfatide, a sulfated galactosylsphingolipid, enhances IAV replication through promoting newly...

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Detalles Bibliográficos
Autores principales: Takahashi, Tadanobu, Takaguchi, Masahiro, Kawakami, Tatsuya, Suzuki, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617187/
https://www.ncbi.nlm.nih.gov/pubmed/23593400
http://dx.doi.org/10.1371/journal.pone.0061092