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Aerosol Exposure to Rift Valley Fever Virus Causes Earlier and More Severe Neuropathology in the Murine Model, which Has Important Implications for Therapeutic Development

Rift Valley fever virus (RVFV) is an important mosquito-borne veterinary and human pathogen that can cause severe disease including acute-onset hepatitis, delayed-onset encephalitis, retinitis and blindness, or a hemorrhagic syndrome. Currently, no licensed vaccine or therapeutics exist to treat thi...

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Detalles Bibliográficos
Autores principales: Reed, Christopher, Lin, Kenny, Wilhelmsen, Catherine, Friedrich, Brian, Nalca, Aysegul, Keeney, Ashley, Donnelly, Ginger, Shamblin, Joshua, Hensley, Lisa E., Olinger, Gene, Smith, Darci R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617210/
https://www.ncbi.nlm.nih.gov/pubmed/23593523
http://dx.doi.org/10.1371/journal.pntd.0002156