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Association of L-Ficolin Levels and FCN2 Genotypes with Chronic Chagas Disease

BACKGROUND: L-ficolin (encoded by FCN2) binds to acetylated sugar moieties of many pathogens, including Trypanosoma cruzi, promoting their phagocytosis and lysis by the complement system. METHODS: We investigated L-ficolin levels in 160 T. cruzi infected patients with chronic Chagas disease and 71 h...

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Detalles Bibliográficos
Autores principales: Luz, Paola R., Boldt, Angelica B. W., Grisbach, Caroline, Kun, Jürgen F. J., Velavan, Thirumalaisamy P., Messias-Reason, Iara J. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617223/
https://www.ncbi.nlm.nih.gov/pubmed/23593180
http://dx.doi.org/10.1371/journal.pone.0060237