Natural IgG Autoantibodies Are Abundant and Ubiquitous in Human Sera, and Their Number Is Influenced By Age, Gender, and Disease

The presence of self-reactive IgG autoantibodies in human sera is largely thought to represent a breakdown in central tolerance and is typically regarded as a harbinger of autoimmune pathology. In the present study, immune-response profiling of human serum from 166 individuals via human protein micr...

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Detalles Bibliográficos
Autores principales: Nagele, Eric P., Han, Min, Acharya, Nimish K., DeMarshall, Cassandra, Kosciuk, Mary C., Nagele, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617628/
https://www.ncbi.nlm.nih.gov/pubmed/23589757
http://dx.doi.org/10.1371/journal.pone.0060726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617628/
https://www.ncbi.nlm.nih.gov/pubmed/23589757
http://dx.doi.org/10.1371/journal.pone.0060726

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