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Synthesis, Characterization, and In Vitro Evaluation of New Ibuprofen Polymeric Prodrugs Based on 2-Hydroxypropyl Methacrylate

The present research work describes the synthesis and evaluation of new acrylic-type polymeric systems having degradable ester bonds linked to ibuprofen as materials for drug delivery. Ibuprofen was linked to 2-hydroxy-propyl methacrylate by an activated ester methodology in a one-pot procedure with...

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Detalles Bibliográficos
Autores principales: Babazadeh, Mirzaagha, Sheidaei, Maryam, Abbaspour, Sara, Edjlali, Ladan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617658/
https://www.ncbi.nlm.nih.gov/pubmed/23641345
http://dx.doi.org/10.3797/scipharm.1204-14