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In Vitro Antileishmanial, Trypanocidal, and Mammalian Cell Activities of Diverse N,N′ -Dihetaryl Substituted Diamines and Related Compounds

The leishmaniasis and Chagas diseases constitute a serious public health problem worldwide with few and ineffective treatment options. The search for new antiparasitic candidates at the initial steps of drug discovery and development is still necessary. The synthesis of 22 de novo synthetized N,N′-d...

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Detalles Bibliográficos
Autores principales: Leal, Sandra M., Amado, Diego F., Kouznetsov, Vladimir V., Escobar, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617668/
https://www.ncbi.nlm.nih.gov/pubmed/23641328
http://dx.doi.org/10.3797/scipharm.1205-14