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Investigation of depth-resolved nanoscale structural changes in regulated cell proliferation and chromatin decondensation

We present depth-resolved spatial-domain low-coherence quantitative phase microscopy, a simple approach that utilizes coherence gating to construct a depth-resolved structural feature vector quantifying sub-resolution axial structural changes at different optical depths within the sample. We show th...

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Detalles Bibliográficos
Autores principales: Uttam, Shikhar, Bista, Rajan K., Staton, Kevin, Alexandrov, Sergey, Choi, Serah, Bakkenist, Christopher J., Hartman, Douglas J., Brand, Randall E., Liu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617721/
https://www.ncbi.nlm.nih.gov/pubmed/23577294
http://dx.doi.org/10.1364/BOE.4.000596