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Anti-inflammatory agents of the carbamoylmethyl ester class: synthesis, characterization, and pharmacological evaluation

In this study, target compounds 5–12 were synthesized via acid amine coupling of ibuprofen and naproxen with methyl ester derivatives of amino acids, namely, l-proline, sarcosine, l-tyrosine, and l-glutamic acid. When tested for anti-inflammatory activity using the acute carrageenan-induced hind paw...

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Detalles Bibliográficos
Autores principales: Sadek, Bassem, Hamruoni, Amar Mansuor, Adem, Abdu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617817/
https://www.ncbi.nlm.nih.gov/pubmed/23576876
http://dx.doi.org/10.2147/JIR.S39743