Cargando…

Anti-inflammatory agents of the carbamoylmethyl ester class: synthesis, characterization, and pharmacological evaluation

In this study, target compounds 5–12 were synthesized via acid amine coupling of ibuprofen and naproxen with methyl ester derivatives of amino acids, namely, l-proline, sarcosine, l-tyrosine, and l-glutamic acid. When tested for anti-inflammatory activity using the acute carrageenan-induced hind paw...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sadek, Bassem, Hamruoni, Amar Mansuor, Adem, Abdu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617817/ https://www.ncbi.nlm.nih.gov/pubmed/23576876 http://dx.doi.org/10.2147/JIR.S39743

Ejemplares similares

Synthesis and Fungicidal Activity of 1-(Carbamoylmethyl)-2-aryl-3,1-benzoxazines
por: Tang, Zi-Long, et al.
Publicado: (2017)

Synthesis, characterization and pharmacological evaluation of pyrazolyl urea derivatives as potential anti-inflammatory agents
por: Somakala, Kanagasabai, et al.
Publicado: (2017)

Resveratrol-based cinnamic ester hybrids: synthesis, characterization, and anti-inflammatory activity
por: Ruan, Ban-Feng, et al.
Publicado: (2017)

Advancement of the 5-Amino-1-(Carbamoylmethyl)-1H-1,2,3-Triazole-4-Carboxamide Scaffold to Disarm the Bacterial SOS Response
por: Selwood, Trevor, et al.
Publicado: (2018)

Betulinic Acid-Azaprostanoid Hybrids: Synthesis and Pharmacological Evaluation as Anti-inflammatory Agents
por: Khlebnicova, Tatyana S., et al.
Publicado: (2020)

Synthesis, Characterization, and Antimicrobial Evaluation of Oxadiazole Congeners
por: Sadek, Bassem, et al.
Publicado: (2011)

Molecular modeling, synthesis, characterization and pharmacological evaluation of benzo[d]oxazole derivatives as non-steroidal anti-inflammatory agents
por: Shakya, Ashok K., et al.
Publicado: (2016)

Synthesis and pharmacological evaluation of pyrazolopyrimidopyrimidine derivatives: anti-inflammatory agents with gastroprotective effect in rats
por: Karoui, Amine, et al.
Publicado: (2013)

New pentadienone oxime ester derivatives: synthesis and anti-inflammatory activity
por: Li, Qin, et al.
Publicado: (2017)

Synthesis and characterization of a new class of anti-angiogenic agents based on ruthenium clusters
por: Nazarov, Alexey A., et al.
Publicado: (2013)

Plant Extracts and Phytochemicals Targeting α-Synuclein Aggregation in Parkinson's Disease Models
por: Javed, Hayate, et al.
Publicado: (2019)

Synthesis and Pharmacological Properties of Novel Esters Based on Monoterpenoids and Glycine
por: Nesterkina, Mariia, et al.
Publicado: (2017)

Synthesis and biological evaluation of dithiocarbamate esters of parthenolide as potential anti-acute myelogenous leukaemia agents
por: Ding, Yahui, et al.
Publicado: (2018)

Synthesis of Functionalized δ‐Hydroxy‐β‐keto Esters and Evaluation of Their Anti‐inflammatory Properties
por: Grosse, Michel, et al.
Publicado: (2022)

Synthesis and Pharmacological Properties of Novel Esters Based on Monocyclic Terpenes and GABA
por: Nesterkina, Mariia, et al.
Publicado: (2016)

Synthesis, comparative docking, and pharmacological activity of naproxen amino acid derivatives as possible anti-inflammatory and analgesic agents
por: Elhenawy, Ahmed A, et al.
Publicado: (2019)

Synthesis and pharmacological evaluation of choroquine derivatives bearing long aminated side chains as antivirus and anti-inflammatory agents
por: Song, Zilan, et al.
Publicado: (2021)

Synthesis and Characterization of Celecoxib Derivatives as Possible Anti-Inflammatory, Analgesic, Antioxidant, Anticancer and Anti-HCV Agents †
por: Küçükgüzel, Ş. Güniz, et al.
Publicado: (2013)

Current and Emerging Classes of Pharmacological Agents for the Management of Hypertension
por: Ojha, Utkarsh, et al.
Publicado: (2021)

Synthesis and quantitative structure–activity relationship study of substituted imidazophosphor ester based tetrazolo[1,5-b]pyridazines as antinociceptive/anti-inflammatory agents
por: Abdou, Wafaa M, et al.
Publicado: (2013)

Synthesis of Certain Pyrimidine Derivatives as Antimicrobial Agents and Anti-Inflammatory Agents
por: Mohamed, Mosaad S., et al.
Publicado: (2010)

Diversity of Chromanol and Chromenol Structures and Functions: An Emerging Class of Anti-Inflammatory and Anti-Carcinogenic Agents
por: Wallert, Maria, et al.
Publicado: (2020)

Synthesis and biological evaluation of a novel class of curcumin analogs as anti-inflammatory agents for prevention and treatment of sepsis in mouse model
por: Zhao, Chengguang, et al.
Publicado: (2015)

Salivary gland derived peptides as a new class of anti-inflammatory agents: review of preclinical pharmacology of C-terminal peptides of SMR1 protein
por: Mathison, Ronald D, et al.
Publicado: (2010)

Pharmacological and Molecular Insight on the Cardioprotective Role of Apigenin
por: Thomas, Shilu Deepa, et al.
Publicado: (2023)

Anti-Inflammatory and Anticoagulant Activities of Synthesized NSAID Prodrug Esters
por: Abualhasan, Murad N., et al.
Publicado: (2020)

Synthesis, characterization, and molecular modeling of phenylenediamine-phenylhydrazine-formaldehyde terpolymer (PPHF) as potent anti-inflammatory agent
por: Mujafarkani, N., et al.
Publicado: (2023)

Repurposing Dimethyl Fumarate for Cardiovascular Diseases: Pharmacological Effects, Molecular Mechanisms, and Therapeutic Promise
por: Thomas, Shilu Deepa, et al.
Publicado: (2022)

Synthesis and Evaluation of Saccharide-Based Aliphatic and Aromatic Esters as Antimicrobial and Antibiofilm Agents †
por: Campana, Raffaella, et al.
Publicado: (2019)

Design, Synthesis and Preliminary Pharmacological Evaluation of New Non-Steroidal Anti-Inflammatory Agents Having a 4-(Methylsulfonyl) Aniline Pharmacophore
por: Mahdi, Monther Faisel, et al.
Publicado: (2012)

Synthesis, Characterization, Antibacterial and Antifungal Evaluation of Novel Monosaccharide Esters
por: Shen, Yi, et al.
Publicado: (2012)

Synthesis, Characterization, and Energetic Properties of Nitrate Ester Acrylate Polymer
por: Kuehl, Valerie A., et al.
Publicado: (2023)

Pharmacological investigations of new galantamine peptide esters
por: Tsvetkova, Dobrina, et al.
Publicado: (2014)

Synthesis and pharmacological characterization of potent, selective, and orally bioavailable isoindoline class dipeptidyl peptidase IV inhibitors
por: Kato, Noriyasu, et al.
Publicado: (2011)

Synthesis and biological evaluation of tricyclic matrinic derivatives as a class of novel anti-HCV agents
por: Tang, Sheng, et al.
Publicado: (2017)

Synthesis, solubility, plasma stability, and pharmacological evaluation of novel sulfonylhydrazones designed as anti-diabetic agents
por: Zapata-Sudo, Gisele, et al.
Publicado: (2016)

Pharmacological basis of the use of the root bark of Zizyphus nummularia Aubrev. (Rhamnaceae) as anti-inflammatory agent
por: Ray, Sarbani Dey, et al.
Publicado: (2015)

Potential Anti-Coronavirus Agents and the Pharmacologic Mechanisms
por: Yang, Yang, et al.
Publicado: (2021)

Novel N-phenylcarbamothioylbenzamides with anti-inflammatory activity and prostaglandin E(2) inhibitory properties
por: Limban, Carmen, et al.
Publicado: (2013)

Efficient Synthesis and Anti-Fungal Activity of Oleanolic Acid Oxime Esters
por: Zhao, Hanqing, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_8uor8k9lav85bikrg41g8k5qbj