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ETHNOPRED: a novel machine learning method for accurate continental and sub-continental ancestry identification and population stratification correction
BACKGROUND: Population stratification is a systematic difference in allele frequencies between subpopulations. This can lead to spurious association findings in the case–control genome wide association studies (GWASs) used to identify single nucleotide polymorphisms (SNPs) associated with disease-li...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618021/ https://www.ncbi.nlm.nih.gov/pubmed/23432980 http://dx.doi.org/10.1186/1471-2105-14-61 |