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Trace determination of lenalidomide in plasma by non-extractive HPLC procedures with fluorescence detection after pre-column derivatization with fluorescamine

BACKGROUND: Lenalidomide (LND) is a new potent drug used for treatment of multiple myeloma. For its pharmacokinetic studies and therapeutic monitoring, a proper analytical method was required. RESULTS: In this study, a non extractive and simple pre-column derivatization procedures have been proposed...

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Detalles Bibliográficos
Autores principales: Khalil, Nasr Y, Darwish, Ibrahim A, Wani, Tanveer A, Al-Majed, Abdel-Rahman A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618069/
https://www.ncbi.nlm.nih.gov/pubmed/23497635
http://dx.doi.org/10.1186/1752-153X-7-52