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Trace determination of lenalidomide in plasma by non-extractive HPLC procedures with fluorescence detection after pre-column derivatization with fluorescamine
BACKGROUND: Lenalidomide (LND) is a new potent drug used for treatment of multiple myeloma. For its pharmacokinetic studies and therapeutic monitoring, a proper analytical method was required. RESULTS: In this study, a non extractive and simple pre-column derivatization procedures have been proposed...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618069/ https://www.ncbi.nlm.nih.gov/pubmed/23497635 http://dx.doi.org/10.1186/1752-153X-7-52 |