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Glycogen Synthase Kinase-3 Inhibition Enhances Translation of Pluripotency-Associated Transcription Factors to Contribute to Maintenance of Mouse Embryonic Stem Cell Self-Renewal

Maintenance of embryonic stem cell (ESC) self-renewal and pluripotency are controlled by extrinsic factors, molecular signaling pathways and transcriptional regulators. While many of the key players have been studied in depth, how the molecular signals interact with transcription factors of the plur...

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Detalles Bibliográficos
Autores principales: Sanchez-Ripoll, Yolanda, Bone, Heather K., Owen, Tom, Guedes, Ana M. V., Abranches, Elsa, Kumpfmueller, Benjamin, Spriggs, Ruth V., Henrique, Domingos, Welham, Melanie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618116/
https://www.ncbi.nlm.nih.gov/pubmed/23577087
http://dx.doi.org/10.1371/journal.pone.0060148