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Dynein and Dynactin Leverage Their Bivalent Character to Form a High-Affinity Interaction
Cytoplasmic dynein and dynactin participate in retrograde transport of organelles, checkpoint signaling and cell division. The principal subunits that mediate this interaction are the dynein intermediate chain (IC) and the dynactin p150(Glued); however, the interface and mechanism that regulates thi...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618186/ https://www.ncbi.nlm.nih.gov/pubmed/23577064 http://dx.doi.org/10.1371/journal.pone.0059453 |