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Dynein and Dynactin Leverage Their Bivalent Character to Form a High-Affinity Interaction

Cytoplasmic dynein and dynactin participate in retrograde transport of organelles, checkpoint signaling and cell division. The principal subunits that mediate this interaction are the dynein intermediate chain (IC) and the dynactin p150(Glued); however, the interface and mechanism that regulates thi...

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Detalles Bibliográficos
Autores principales:	Siglin, Amanda E., Sun, Shangjin, Moore, Jeffrey K., Tan, Sarah, Poenie, Martin, Lear, James D., Polenova, Tatyana, Cooper, John A., Williams, John C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618186/ https://www.ncbi.nlm.nih.gov/pubmed/23577064 http://dx.doi.org/10.1371/journal.pone.0059453

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